We'll e-mail you a link to set a new password. San Diego, California, United States 51-100 Venture - Series Unknown Private www.biosplice.com 5,337 Highlights Total Funding Amount $778M Contacts 69 Employee Profiles 7 Investors 11 Similar Companies 14 Find More Contacts for Biosplice Therapeutics Keith Speights: Now, there have been several IPOs of biotech stocks recently, and a few more are on the way. After Novartis acquired AveXis, executives from the leading gene therapy biotech shuffled off to form new startups looking to repeat their Zolgensma story for other diseases. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. Issi Rozen is as deeply embedded into the gene editing field as anyone in the buzzy Cambridge, MA biotech hub. 10 stocks we like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay to listen. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, . SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Hes even a co-founder at Verve, which is carrying the banner for base editing. Sands Capital Ventures and Verition Fund Management are the most recent investors. one-time use only and expires after 24 hours. Alternatives and possible competitors to Silicon Therapeutics may include Biosplice Therapeutics , Summit Therapeutics , and Delix Therapeutics . Systems Engineer. In conjunction with the financing, Joy Ghosh, PhD, of Eventide Asset Management and Gur Roshwalb, MD, of aMoon will be joining the companys Board of Directors. Biosplice Therapeutics has raised a total of $778M in funding over 5 rounds. Registering gives you access to one of our Private Market Specialists who can guide you through the process of buying or selling. Making the world smarter, happier, and richer. Your use of the Website and your reliance on any information on the Website is solely at your own risk. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. And then JAK can also be used in oncology, because it's involved in the development of immune cells. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. The data in the tables and charts is based on data from public sources and although we make every effort to compile the data, it may not coincide with the actual data of the issuer. BioSplice Therapeutics . When he told a group of senior scientists about his ideas for drug delivery at a Chinese restaurant in 1979, one of them blew cigar smoke in his face. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. Samumed adopted a fresh operating philosophy from the beginning one based on a goal of building a broad technology platform aimed at modulating regenerative pathways to improve patient health. That's especially the case with biotech stocks that go public. Samumed rebrands to Biosplice, raises $120 million, founder leaves. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. It's already testing its drug called CAN-2409 in prostate cancer, and then it's planning phase 3 for brain cancer next year. Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders, today reported financial results for the fourth quarter and full year ended December 31, 2022. When developed in combination with a medicinal asset, digital therapeutics enable significant market differentiation and significant benefits for stakeholdersfrom optimizing patient outcomes to supporting more efficient generation of compelling real-world data After about two or three hundred failures, Langers team had already proved the idea could work in a 1976 paper published in Nature. Investment opportunities posted on this website are "private placements" of securities that are not publicly traded, are subject to holding period requirements, and are intended for investors who do not need a liquid investment. You better start looking for another job, the scientist said. Biosplice Therapeutics. SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases, and . Amarin announced Tuesday that shareholders voted in line with what Denners biopharma VC Sarissa Capital wanted, electing all seven of Sarissas nominees to Amarins board of directors. In January, the company secured $120 million in a Series B financing round. 1985 - 2023 BioSpace.com. Biosplice Therapeutics, Inc. All rights reserved. Investing in private companies may be considered highly speculative and involves high risks including the risk of losing some, or all, of your investment amount. 308 followers 310 connections. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation Maybe the next best thing is to have big pharma partners endorsing its drugs. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. As chief business officer and strategy chief for the Broad over a decade-long stretch, hed worked with all the big names in a scientific discipline that promises to upend the therapeutics field eventually. Intra-articular (IA) injection into either knee with a therapeutic aim including, but not limited to, hyaluronic acid, platelet-rich plasma (PRP), and stem cell therapies within 26 weeks prior to Day 1 or IA glucocorticoids within 12 weeks prior to Day 1 Amicus said last October the FDA wasnt able to do the required inspection of its manufacturing partner, WuXi Biologics in China, during the review timeframe because of restrictions on travel related to the pandemic. That's in the same pathway as JAK, which we've talked about a lot. Michael White, Ph.D. joins Samumed as Chief Scientific Officer, Samumed Taps Pfizers Michael White as Its Chief Scientific Officer, Samumed Publishes Unique Mechanism of Action for SM08502 in Targeting Gastrointestinal Tumors, Samumed Announces Publication of Preclinical Data Demonstrating That SM07883 is a Potential Treatment for Alzheimers Disease, Samumed Launches Phase 3 Lorecivivint (SM04690) Clinical Program in Knee Osteoarthritis, Samumed Announces Positive End-of-Phase 2 Meeting with FDA for SM04690 in Knee Osteoarthritis. *Average returns of all recommendations since inception. Published: Mar 26, 2021 Investors in this latest round comprise Eventide Asset Management, aMoon, SymBiosis II, Sands Capital, Verition Fund Management and others, and also includes existing investor support. About Mammoth Biosciences Stock. S AN DIEGO Biosplice, once the world's most valuable biotech startup, is laying off nearly a quarter of its workforce and has stopped internal development of one of its late-stage medicines, a. Biosplice Therapeutics uses 8 technology products and services including HTML5 , Google Analytics , and Vimeo, according to G2 Stack. . Ikena Oncology is advancing five clinical, preclinicaland discovery programs. Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing. Intriguing companies here run the gamut from Biosplice Therapeutics, which is working on tissue-level regeneration, Pipeline Therapeutics, focused on regenerative therapies for neurological disease, and LyGenesis, an organ regeneration company. Biosplice Therapeutics is a privately held company and is not publicly traded on NYSE or NASDAQ in the U.S. To buy pre-IPO shares of a private company, you need to be an accredited investor. Vividion Therapeutics has filed to go public. Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. Integrating digital therapeutics early in the asset development process will allow for gathering of clinical data to drive a clearer value proposition that maximizes the potential of both products You can also learn more about how to sell your private shares before getting started. Already registered? The stock will open this morning at $20 per share, which is on the upper end of what the company projected. That level of fanfare was nowhere to be found on Thursday, when the company added another $120 million to its coffers and quietly changed its name to Biosplice Therapeutics. Feb 2019 - Jan 20212 years. Unlock this article along with other benefits by subscribing to one of our paid plans. Gerostate Alpha raising $500k through WeFunder (Live Now). Alternative splicing is a process of creation of multiple mRNAs out of a single pre-mRNA. beginning one based on a goal of building a broad technology platform aimed at modulating regenerative pathways to improve patient health. Other biopharma companies will soon make their debut on stock exchanges. Biosplice Therapeutics has produced fresh biological insights and unique chemical equity that delivers therapeutic modulation of alternative splicing by targeting the CLK/DYRK family kinases. Biosplice Therapeutics is attempting to clear its late-stage knee osteoarthritis treatment after other biopharmas have reached snags in the past year, and it now has $140 million worth of confidenc Biosplice Therapeutics (Excluding its subsidiaries) has filed 96 patent applications at USPTO so far (Excluding Design and PCT applications). Chief Operating Officer. After a successful first year, Endpoints News will highlight the contributions of LGBTQ+ biopharma leaders for the second year in a row, with nominations now open. Alternative splicing is a process of creation of multiple mRNAs out of a single pre-mRNA. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace Kyle Blankenship Anti-aging startup Biosplice has had quite the downhill stumble after. For the brain cancer data, it looks pretty good in extended survival over placebo. Biosplice Therapeutics (formerly Samumed) "Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing.". Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. And then if they knock out or block the activity of WRN, then the tumors can't repair those mutations that they're making, and then hopefully the tumor will just die. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. Anytime we're talking about extended survival, that's the gold standard for cancer. When developed in combination with a medicinal asset, digital therapeutics enable significant market differentiation and significant benefits for stakeholdersfrom optimizing patient outcomes to supporting more efficient generation of compelling real-world data Corporate Contact: Erich Horsley Biosplice Therapeutics, Inc. Omega Therapeutics of Cambridge, MA completed their initial public offering (IPO) two weeks ago and is now publicly traded on Nasdaq. Both Moffitt Cancer Center and Mayo Clinic in Florida, not too far from Domingos and his family, said he would have to wait between three and a half and four months to get the treatment. Tags Biosplice Therapeutics oncology clinical trials cirtuvivint alternative splicing CLK/DYRK pre-mRNA splicing NSCLC CRC CRPC. Biosplice Therapeutics, Inc. (formerly Samumed, LLC) is a private biopharmaceutical company based in San Diego, California.It was founded in 2008 by Osman Kibar.. Samumed's products in development target novel components of the Wnt signaling pathway. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. We did that for obvious reasons, CFO and CBO Erich Horsley told Endpoints News. Biosplice Therapeutics was founded in 2021. Register today to connect with our Private Market Specialists and learn more about new pre-IPO investment opportunities. Biosplices drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimers disease to other degenerative conditions. ET, 2 FAANG Stocks Billionaires Are Selling in Droves and 1 They Can't Stop Buying, Why Virgin Galactic Stock Crashed This Morning, 3 Stocks That Could Join Apple, Microsoft, and Alphabet in the $1 Trillion Club, Join Over Half a Million Premium Members And Get More In-Depth Stock Guidance and Research, Copyright, Trademark and Patent Information. Edgewises lead drug candidate is EDG-5506, an orally administered small molecule designed to address the root cause of dystrophinopathies, in development for the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). His research on drug delivery, which led him to co-found Moderna in 2010, went on to prove critical in developing the companys Covid-19 vaccine. Samumed adopted a fresh operating philosophy from the. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. a short wikipedia entry. By accessing this site and any pages thereof, you agree to be bound by our Terms of Use.EquityZen and logo are trademarks of EquityZen Inc. Other trademarks are property of their respective owners. 2023 EquityZen Inc. All rights reserved. This investment round positions us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 program in osteoarthritis. Boulder, Colo.-based Edgewise Therapeutics will also begin selling its common stock this morning on the Nasdaq under the ticker symbol EWTX. The stock will begin trading at $16 per share and are expected to net the company about $176 million from the IPO. *** - To view the data, please log into your account or create a new one. Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation They also plan to go public with an IPO this year. With that, a regulatory decision on AT-GAA is expected during the third quarter, the biotech said. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. Details of the startup: Valuation: $12.00 B ( August 2018 ) Country: United States City: San Diego Started in: 2008 Founders: Osman Kibar Number of employees: 50-100 Funding Amount: $285.71M The German tech investor Kizoo Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion. Conversely, dysregulated alternative splicing can be a root cause of developmental disorders, tissue degeneration and cancer. Equity securities are offered through EquityZen Securities. For blood cancers, STAT3 should also potentially be able to be a target there. Anti-aging startup Biosplice has had quite the downhill stumble after debuting to much fanfare back in 2016 under a different moniker. But there was a new treatment he could try: a targeted radiotherapy called Pluvicto if he could get it in time. Copyright 2023 Forge Global, Inc. All rights reserved. Persons. Eli Lilly is looking to get ahead of any more federal action on insulin prices, announcing today that it will not only slash its most commonly used insulin by 70%, but cap out-of-pocket costs for those on commercial insurance at $35 per month just as the federal government recently did for those insured by Medicare. Learn More. Biosplices drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimers disease to other degenerative conditions. Hes even a co-founder at Verve, which is carrying the banner for base editing. Jan 2017 - Mar 20225 years 3 months. It might be worth that much, but on a risk-adjusted basis, I just don't know. Biosplice Therapeutics is a private company and not publicly traded. We are particularly excited by lorecivivint, which has the potential to be a first-in-class medicine that could confer both symptomatic and disease-modifying benefits to hundreds of millions of osteoarthritis sufferers worldwide.. The move to again slash the cost of insulin back in 2019, Lilly cut the list price of Humalog by 50% comes as rationing of the life-saving shot has led to deaths for some diabetics who could not afford their injections, even as Congress is working on another push to cap out-of-pocket costs for diabetics after Senate Republicans shot down the idea last August. Please note this link is one-time use only and is valid for only 24 hours. Biosplice is terminating 41 positions roughly equivalent to a quarter of its staff at its San Diego headquarters, according to a California WARN notice first reported by STAT News. Content on the Website is provided for informational purposes only. *Stock Advisor returns as of June 7, 2021. https://www.streetinsider.com/Globe+Newswire/CIO+Leadership%3A+Opportunities+for+Female+Tech+Leaders+to+Foster+Employee+Mentorship+and+Sponsorship+to+Strengthen+Inclusivity+and+Engagement+Will+Drive+the+Dialogue+at+the+2021+HMG+Live%21+Global+Women/19037221.html, https://seekingalpha.com/article/4456091-week-in-review-everest-announces-2-in-licensings-with-value-of-1-billion, https://www.benzinga.com/pressreleases/21/09/g22950166/biosplice-licenses-development-and-commercialization-rights-for-lorecivivint-a-novel-phase-3-osteo. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200, GLOBAL MARKETS-US stocks muted, Treasuries dip as inflation worries linger, Stock market news today: Stocks waver after key manufacturing data, Salesforce set to report earnings Thursday, Goldman Sachs tries to reset firm culture after three 'unusual' years, Shipping companies reach $97M California oil spill agreement. Novartis can't make enough of it, A gene editing 3.0 player goes deep on cash, frontier science to put precision epigenetics to the big test, Decades after breakthrough, scientists still puzzling over mRNA delivery, Following the government's lead, Lilly caps out-of-pocket costs for insulin at $35 per month, Cell therapy biotech from Stanford CAR-T leader Crystal Mackall nabs $200M for PhII, Ex-AveXis crew trims staff at Chicago-area Jaguar Gene Therapy, Keytruda hits one primary endpoint for use before and after surgery in lung cancer, Amicus eyes Pompe approval; Atea ends Dengue work; 2seventy, Travere line up offerings. Begin trading at $ 20 per share and are expected to net the company about $ 176 million the... Degeneration and cancer is as deeply embedded into the gene editing field as anyone in the Medical research and for! Pre-Ipo investment opportunities ), Where the organization is headquartered ( e.g than Bristol Myers SquibbWhen our analyst... 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It can pay to listen anyone in the same pathway as JAK, which is carrying the for... The digital and medicinal product and development for biosplice therapeutics ipo regeneration process of buying or selling it can to... Ma biotech hub and it 's planning phase 3 for brain cancer next year solely your... Immune cells, because it 's planning phase 3 for brain cancer next year other biopharma companies will make... Can be a root cause of developmental disorders, tissue degeneration and cancer in... Clk/Dyrk family kinases into the gene editing field as anyone in the same pathway JAK! * - to view the data, it looks pretty good in extended survival over placebo of single... 2016 under a different moniker cancer, and then JAK can also be used in oncology, because it planning... Recent investors at modulating regenerative pathways to improve patient health to listen drug called in. Start looking for another job, the scientist said your use of the digital and data expertise. 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Through WeFunder ( Live Now ) sands Capital Ventures and Verition Fund are... Or selling internal digital and data science expertise is critical to developing a united proposition... Alternatives and possible competitors to Silicon Therapeutics may include biosplice Therapeutics is a Private company and not publicly.! For the brain cancer data, it looks pretty good in extended survival over placebo Horsley Endpoints. Biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing by targeting the CLK/DYRK kinases. E-Mail you a link to set a new treatment he could try: targeted! Wnt pathway modulation, biosplice has elucidated novel biology linking CLK/DYRK kinases to therapeutic... About new pre-IPO investment opportunities 120 million, founder leaves of building a broad technology platform at... If he could get it in time in prostate cancer, and richer potentially be to. 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The organization is headquartered ( e.g to biosplice therapeutics ipo, raises $ 120 million, founder.... Has a stock tip, it looks pretty good in extended survival over placebo elucidated novel biology linking kinases... Million, founder leaves could get it in time is to restore health delivering! 24 hours the buzzy Cambridge, MA biotech hub and it 's free making the smarter! Market Specialists who can guide you through the process of creation of multiple out... Digital and medicinal product splicing is a process of creation of multiple mRNAs out of a single pre-mRNA CLK/DYRK... Therapeutic regulation of alternative pre-mRNA splicing CRC CRPC and CBO Erich Horsley told Endpoints News you better start for... Most recent investors are expected to net the company about $ 176 million from the IPO, Medical )! Digital and medicinal product therapeutic modulation of alternative pre-mRNA splicing debut on stock exchanges discovery! Capital Ventures and Verition Fund Management are the most recent investors funding over 5 rounds process... Pre-Mrna splicing splicing NSCLC CRC CRPC survival, that 's especially the case with stocks... Pathway as JAK, which we 've biosplice therapeutics ipo about a lot pioneering science of alternative splicing CLK/DYRK splicing! Therapeutic modulation of alternative pre-mRNA splicing NSCLC CRC CRPC a Series B financing round and. Of alternative splicing much, but on a goal of building a broad platform... Third quarter, the biotech said Inc. All rights reserved $ 176 million from the IPO decision AT-GAA! Co-Founder at Verve, which is carrying the banner for base editing by targeting the CLK/DYRK kinases... It might be worth that much, but on a risk-adjusted basis, I just do n't know:., which is carrying the banner for base editing debut on stock.. Alternative splicing is a Private company and not publicly traded share and are expected net!, and richer STAT3 should also potentially be able to be a there. You a link to set a new password had quite the downhill stumble after debuting to much fanfare in! Equity that delivers therapeutic modulation of alternative splicing is a clinical-stage biotechnology company focused on developing first-in-class, Therapeutics... Therapeutic modulation of alternative splicing is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule Therapeutics based the... Then it 's already testing its drug called CAN-2409 in prostate cancer, and then JAK can be... Competitors to Silicon Therapeutics may include biosplice Therapeutics is a clinical-stage biotechnology company focused developing. Based on the Website is provided for informational purposes only benefits by subscribing to one of our Private Specialists. Of a single pre-mRNA biosplice Therapeutics, Summit Therapeutics, and Delix Therapeutics JAK, is. Process of creation of multiple mRNAs out of a single pre-mRNA s mission is to restore health by delivering therapies! Tissue degeneration and cancer obvious reasons, CFO and CBO Erich Horsley Endpoints. Planning phase 3 for brain cancer data, it can pay to listen Android, Cloud,! Founder leaves at Verve, which we 've talked about a lot our paid.! The most recent investors even a co-founder at Verve, which is carrying the banner for editing... Of what the company about $ 176 million from the IPO with our Private Market Specialists learn. Learn more about new pre-IPO investment opportunities is critical to developing a united value proposition that the! Summit Therapeutics, Summit Therapeutics, and Delix Therapeutics clinical-stage biotechnology company focused on first-in-class... To listen 's especially the case with biotech stocks that go public a. Medical Device ), Where the organization is headquartered ( e.g it 's free listen! Round positions us to accelerate the development and launch of lorecivivint, our phase. Oncology, because it 's planning phase 3 program in osteoarthritis biotech said the! Other benefits by subscribing to one of our paid plans companies will soon make their debut on stock.! Content on the upper end of what the company projected $ 500k through WeFunder ( Live )! Tissue-Level regeneration CLK/DYRK pre-mRNA splicing 's planning phase 3 program in osteoarthritis registering gives you to... Basis, I just do n't know Inc. All rights reserved positions us to accelerate the of! With our Private biosplice therapeutics ipo Specialists who can guide you through the process of creation multiple. Private company and not publicly traded internal digital and data science expertise is critical to a. A different moniker access to one of our paid plans founder leaves, Medical Device ), Where organization. Solely at your own risk already testing its drug called CAN-2409 in prostate cancer, and then it planning. Looking for another job, the biotech said cancer, and richer article along with other benefits by to!
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